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MesoSPIMs: Custom-built microscopes that can scan individual neurons in the brain

MesoSPIMs are open-source light-sheet microscopes for imaging cleared tissue.

The custom-built microscopes enabled scientists to look at individual neurons using sheets of light rather than cutting a brain into slices.

The mesoSPIM Initiative paves the way for future discovery and understanding of the brain’s complex organization. The studies may one day reveal vital information on what drives mental illnesses and addictions.

By Wells Baum

Wells Baum is a daily blogger and curious explorer of the world who connects the dots between life, arts, and knowledge.

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