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MesoSPIMs: Custom-built microscopes that can scan individual neurons in the brain

MesoSPIMs:Custom builtmicroscopesthatcanscanindividualneuronsinthebrain

MesoSPIMs are open-source light-sheet microscopes for imaging cleared tissue.

The custom-built microscopes enable scientists to look at individual neurons using sheets of light rather than cutting a brain into slices.

The mesoSPIM Initiative paves the way for the future discovery and understanding of the brain’s complex organization. The studies may one day reveal vital information on the neuronal networks that drive mental illnesses and addictions.

A chicken embryo captured under the mesoSPIM microscope
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